Novella Clinical

Novella Clinical Overview

We offer our services at a range of levels, including: previews to provide a smallsample of images for initial assessment, automated data collection to obtainstatistically valid datasets, and several types of advanced analysis forparticle characterization or three-dimensional reconstruction. TEM imaging using negative stain or cryoEM – liposomes, viruses, VLPs, largemacromolecules, cell free systems. Particle characterization – statistical analysis of particle size and morphology. 3D reconstructions– thousands of automatically acquired images or arbitrarily oriented, identicalparticles are combined to construct a detailed 3D model. Signal averaging inherent in the procedureprovides dramatic improvements in image contrast and noise levels.